Hiya!
Well...because I'm new to the Pearl and moving on from my older phone, a Sidekick 3, I hold onto the Pearl with both hands and type with both thumbs, just as I did with the Sidekick. It's a little more tricky with the Pearl compared to the Sidekick (or any QWERTY cell phone keyboard, I guess) because you have less space to work with. I've had to deal with my thumbs bumping into each other the first few times I worked with the Pearl. :P But I'm beginning to get the hang of typing with both thumbs. Mostly, it helps to remember that AutoText is my friend--I've taken a lot of netspeak abbreviations and my own abbreviations from my Sidekick and put them into the Pearl's AutoText settings, so that helps make life a lot easier for me.