I've had those before...after a new install to 4.0.2 for BESN. It seems that the BES polling of the users' mail file conflicts with other normal Domino related tasks. In my case it always seem to start around 1:00Am -> 2:00AM on some mornings, for some users. That's when the usual domino server tasks run - update, designer e.g. -
This translated into APB messages being generated for those users affected. Eventually we had to apply some hotfixes which didn't get rid of it entirely at first, but they seem to have gone away now.
A couple of things to try....compact, fixup and updall...on some of the affected users.
Also do a check on the hotfixes and latest service packs for your BES version to see what's applicable to the described problem.
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